Understanding latent tuberculosis: the key to improved diagnostic and novel treatment strategies
نویسندگان
چکیده
منابع مشابه
Latent M. tuberculosis infection--pathogenesis, diagnosis, treatment and prevention strategies.
One third of the earths population is infected with Mycobacterium tuberculosis (Mtb), but only 5-10% of the infected individuals develop active tuberculosis (TB) over their lifetime. The remaining 90-95% stay healthy and are called latently infected individuals. They are the biggest reservoir of the tubercle bacilli and identifying the cases of latent TB is a part of the global plan of TB contr...
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متن کاملUnderstanding latent tuberculosis: a moving target.
Tuberculosis (TB) remains a threat to the health of people worldwide. Infection with Mycobacterium tuberculosis can result in active TB or, more commonly, latent infection. Latently infected persons, of which there are estimated to be approximately 2 billion in the world, represent an enormous reservoir of potential reactivation TB, which can spread to other people. The immunology of TB is comp...
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ژورنال
عنوان ژورنال: Drug Discovery Today
سال: 2012
ISSN: 1359-6446
DOI: 10.1016/j.drudis.2011.12.013